ABSTRACT
To determine the role of serum and urine selenium, and boron levels in children with resistant epilepsy. Serum and urine boron and selenium levels were studied in 53 cases [32 boys and 21 girls] diagnosed with resistant epilepsy between April 2006 and February 2007 at the Department of Pediatric Neurology, Erciyes University, Kayseri, Turkey. Differences between groups were assessed using Student's t-test. Countable data were defined as percentage. Inter-group difference was assessed by Chi-square test. P-values less than 0.05 were considered significant. When serum and urine boron and selenium levels were evaluated and compare with controls, a statistically significant difference was found in serum selenium, urine selenium, and urine boron levels [p<0.05]. No significant difference was found in serum boron levels [p>0.05]. It was observed that there is a need for selenium supplementation in treatment of patients with resistant epilepsy, while no etiologic role is observed for boron